Journal: Stem Cell Research & Therapy
Article Title: Comparison of adipose tissue- and bone marrow- derived mesenchymal stem cells for alleviating doxorubicin-induced cardiac dysfunction in diabetic rats
doi: 10.1186/s13287-015-0142-x
Figure Lengend Snippet: Retrograde Langendorff perfusion was performed on isolated hearts at the end of the study (12 weeks after streptozotocin ( STZ ) injection) to measure a heart rate, b left ventricular developed pressure ( LVDP ), c LVSP, d left ventricular end diastolic pressure ( LVEDP ), e maximum rate of pressure rise ( dp/dt max ) and f rate pressure product ( RPP ) in different groups. Data are mean ± SD. @ P <0.05 compared to respective controls at time points, ▲ P <0.05 compared to the untreated STZ + doxorubicin ( STZ + DOX ) group. BM-MSCs bone marrow-derived mesenchymal stem cells, AT-MSCs adipose tissue-derived mesenchymal stem cells
Article Snippet: The ascending aorta was then cannulated and placed along the perfusion line of non-recirculating constant-flow Langendorff apparatus (Radnotti, Harvard apparatus, USA).
Techniques: Isolation, Injection, Derivative Assay